Protein Modification Reagents
=O)[N+]([O-])=O | 1g | 112541436](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502202925.JPG-250.jpg)
eMolecules 1353011-89-8 | DNP-PEG2-acid | Broadpharm | MFCD20926369 | 343.292 | C13H17N3O8 | 98.000 | OC(=O)CCOCCOCCNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O | 1g | 112541436
DNP-PEG2-acid | Broadpharm | 1353011-89-8 | MFCD20926369 | 343.292 | C13H17N3O8 | 98.000 | OC(=O)CCOCCOCCNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O | 1g | 112541436
Medchemexpress LLC Propargyl-PEG4-sulfonic acid | 1817735-29-7 | 98.0% | 296.34 | 5 G
Propargyl-PEG4-sulfonic acid is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Azide-containing molecules.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Alkyne group
- Facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Medchemexpress LLC Propargyl-PEG4-CH2COOH | 1429934-37-1 | >=97.0% | 290.31 | 50 MG
Propargyl-PEG4-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. PROTACs themselves consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest, enabling selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Alkyne group
- Facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups
- Enables selective degradation of target proteins
Medchemexpress LLC Cholesterol-PEG-MAL | 95.1% | 2000 (average) | 5 MG
Cholesterol-PEG-MAL (MW 2000) is a PEGylated cholesterol derivative bearing a terminal maleimide group. It self-assembles in aqueous media and is used to form liposomes, micelles, and nanoparticles, and to conjugate thiol-containing molecules via maleimide-thiol chemistry. Intended for research use only.
- Reactive maleimide end group enables stable thiol conjugation.
- Amphiphilic cholesterol-PEG structure promotes self-assembly into liposomes and micelles.
- Average molecular weight ~2000 provides steric stabilization in formulations.
- Available in small research quantities suitable for formulation development.
- Documentation available for quality verification and handling.
Medchemexpress LLC DSPE-PEG-FITC | 95.0% | 600 Da (average) | 25 MG
DSPE-PEG-FITC (MW 600) is a fluorescein-labeled PEGylated phospholipid used to introduce surface fluorescence into liposomes and nanoparticles. It is an amphiphilic conjugate that forms micelles in aqueous solution and enables tracking and imaging of lipid-based carriers in biological studies (Ex/Em = 488/525 nm).
- Amphiphilic PEG-lipid that forms micelles in aqueous solution.
- Provides surface fluorescence for liposome and nanoparticle tracking.
- Fluorescein label with excitation/emission 488/525 nm suitable for common fluorescence instruments.
- Average molecular weight about 600 Da for consistent labeling behavior.
- Solid, light yellow material with reported purity ~95.0%.
- Store protected from light; stable frozen in solvent for extended storage.
Medchemexpress LLC Dspe-peg-fitc | 1000788-53-3 | 95.0% | 10 MG
DSPE-PEG-FITC (MW 1000) is a fluorescein-labeled PEGylated phospholipid supplied as a powder. It functions as a fluorescent amphiphile that incorporates into lipid bilayers or forms micelles for labeling liposomes, nanoparticles, and membranes in fluorescence microscopy, flow cytometry, and tracking applications. Manufacturer documentation provides purity, storage, and handling details.
Medchemexpress LLC N3-PEG4-C2-NHS ester | 944251-24-5 | MFCD13184948 | 98.9% | 388.37 g/mol | C15H24N4O8 | 100 MG
N3-PEG4-C2-NHS ester is an azide-terminated polyethylene glycol (PEG4) N-hydroxysuccinimide (NHS) ester used as a bifunctional linker for bioconjugation and click-chemistry applications, including antibody-drug conjugate assembly and labeling of biomolecules.
- Azide functional group enables copper-catalyzed and strain-promoted click reactions.
- NHS ester reacts readily with primary amines to form stable amide bonds.
- Peg4 spacer provides hydrophilicity and conformational flexibility.
- High purity supports reliable research-grade conjugation.
- Stability under recommended cold-storage conditions for long-term use.
Medchemexpress LLC Tos-PEG4-NH-Boc (PROTAC Linker 7) | 1246999-33-6 | >98.0% | 100 MG
Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based linker.
- Used in the synthesis of PROTACs.
- Connects two different ligands.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.